Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep1124 | Thyroid cancer | ECE2016

Adjuvant metformin (M) therapy in differentiated thyroid carcinoma (DTC)

Balestra Margherita , Gay Stefano , Pera Giorgia , Mortara Lorenzo , Monti Eleonora , Giusti Massimo

M shows an antiproliferative effect. In vivo, M reduces TSH in type 2 diabetes mellitus (T2DM) and DTC aggressiveness in DTC with T2DM. The aim of the study was to evaluate in DTC diabetic (Gr1, n=30 under M 1500 mg/day) and non-diabetic without (Gr2, n=83) or under M (gr3, n=84; M 1000 mg/day) the adjuvant role of M. Clinical and laboratory examinations were performed up to 24 months. At baseline the DTC groups were similar for age, gender, tumor st...

ea0041ep1144 | Thyroid cancer | ECE2016

Clinical evaluation and outcome of indeterminate (Thy 3) thyroid nodules

Monti Eleonora , Balestra Margherita , Mortara Lorenzo , Gay Stefano , Pera Giorgia , Adorno Alberto , Giusti Massimo

In thyroid nodules with indeterminate cytology, presurgical evaluations for risk management comprise biochemical tests, ultrasonography (US), elastography-US (USE), contrast-enhanced US (CEUS) and mutation analysis. The cytology of 130 Thy 3 nodules was reviewed according to the BTA 2014 classification. Nodules were divided into Thy 3a and Thy 3f categories. Histology was available in 97 nodules. Malignancy was the final diagnosis in 19% of surgically treated nodules. No signi...